Rupesh J. Parikh, MD

Medical Oncologist

Rupesh J. Parikh, MD

Rupesh J. Parikh, MD is part of Comprehensive Cancer’s medical oncology team that provides world-class cancer care in a supportive and caring environment.

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“Treating the patient, not just the disease”

Dr. Rupesh J. Parikh’s philosophy of taking care of the patient first and the disease second, has led him to become highly regarded and respected in the medical community, serving as the Practice President for Comprehensive Cancer Centers and Chief of Staff for Dignity Health-St. Rose Dominican’s Siena and Rose de Lima campuses.

In addition to his duties as Practice President, Dr. Parikh is a practicing medical oncologist and hematologist at Comprehensive. Since joining Comprehensive in 2005, he has been proactive in the fight against cancer having served as principal investigator for a number of clinical trials. With access to more than 170 clinical trials annually and practice research that has led to more than 100 FDA-approved cancer treatments, Dr. Parikh treats patients who have traveled from out of state as well as many locals. Under Dr. Parikh’s leadership, research staffing at the practice has nearly doubled and there is a continued emphasis on quality as well as continued training and education.

In addition to his work at Comprehensive, Dr. Parikh also strives to give back to the medical community as an Adjunct Assistant Professor for Touro University and Clinical Assistant Professor for UNLV School of Medicine, helping to teach the practitioners of tomorrow. He has authored several publications and currently sits on the Medical Executive Committee, serves as the chairman of the Pharmacy & Therapeutic Committee and is on the Community Board for Dignity Health – St. Rose Hospitals in the Las Vegas/Henderson area.

Prior to joining the practice, Dr. Parikh was the lead researcher for enrolling patients onto clinical trials at Southern California Permanente Medical Group at Kaiser Fontana. He served on the regional cancer committee and was the chairman of the local cancer committee as well.

He is the recipient of numerous notable awards including Inspired Excellence in Healthcare honoree by Las Vegas HEALS, Medical Marvel by Nevada Business Magazine and Health Care Headliner by VEGAS INC. Dr. Parikh also consistently receives Top Doctor recognitions from VEGAS INC Health Care Quarterly, Desert Companion, Vegas Seven and Castle Connolly. He has been recognized as America’s Top Oncologist by the Consumer Research Council of America, America’s Most Honored Professionals by The American Registry, CareDash Five Star Physician as well as Top 10 Oncologists, Top 10 Doctors, Patients’ Choice, Most Compassionate Doctor and On-Time Physician from

Dr. Parikh completed his fellowship in hematology/oncology from The University of Oklahoma, and residency in internal medicine from St. Agnes Hospital, Baltimore where he served as chief resident.

As a hematologist/oncologist he sees all cancer types and has a special interest in the following areas: anemia, breast cancer, chronic leukemia, colon cancer, myeloma, lung cancer, hospice and palliative medicine and clinical research. Dr. Parikh also sees a variety of hematologic malignancies and lymphomas. His extensive research in the leukemia and lymphoma field has been published in Neoplastic Diseases of the Blood, 4th edition.

Internal Medicine
Medical Oncology

American Society of Clinical Oncology
Cancer Treatment Centers of America
Credentialing Committee Member – St. Rose Hospitals
Community Board Member – St. Rose Hospitals
Chief of Staff – Dignity Health-St. Rose Dominican’s Siena and Rose de Lima campuses
Clark County Medical Society
Member of the National Pharmacy & Therapeutic Committee for The US Oncology Network, Nevada Cancer Research Foundation
Nevada Oncology Society
Nevada State Medical Association
US Oncology Research Network

Dr. Parikh is married with children. He is fluent in several languages and enjoys traveling. He also enjoys reading, golfing, teaching, enjoying sports, kite flying and spending time with his family.


“Why I do what I do”:

“Throughout the developmental stages of life, I have come to realize that I will traverse many a crossroad. At all of these junctures, I foresee pain and suffering as always being an inseparable part of the world we live in. The misfortune of the underprivileged has always moved me to do something plausible to ameliorate their situation. This spirit of service to mankind is embedded in to the heart of my commitment to medicine. Finding a path of service to my fellow human beings was not only an idea in my mind, it was a passion in my heart, and for me, the most direct path towards that goal was to become a physician.”

“Treating the Patient, Not Just the Disease”

Sir William Osler wrote many years ago: “the good physician treats the disease; the great physician treats the patient who has the disease…”

When I was asked a couple of months ago on submitting an article for this publication, I initially wanted to write about a particular disease process. But I quickly came to realize that we as physicians often forget the most important part of the picture, the patient, their lives, and their families. I believe that the difference between a mediocre doctor and an outstanding doctor is the ability to treat the whole patient. Good doctors should consider the entire elaborate combination of factors that make each person unique. Realizing this, I give you the reader my own personal view on “treating the patient, and not just the disease.”

What makes someone a good doctor? Knowledge? Compassion? Interaction?

I will share a personal story that changed how I practice medicine. In the year 2000, I started my first transplant rotation, a month into my cancer training. There I met John, a healthy 20 something year old undergoing a bone marrow transplant for his lymphoma, that had relapsed twice before. As I entered his room gowned, gloved, and masked, I could easily sense a level of anxiety that set in his face. It was like he knew that I would be one of many residents that would go through the “routine” of asking him the same series of questions and going through the same rituals of examining him.

A week and then two went by, and to my failure, I was unable to get him to talk, except for the “yes and no” answers to my questions. Every day I left the hospital with the same feeling of emptiness and despair. Then on a Monday morning, I came in to see a new attending physician on the transplant service. Unlike his predecessor, he appeared quite laid back, dressed in jeans and had a ponytail with scruffy hair. He introduced himself as “Dr. Selby” and we started on our routine of rounding on the patients. John was first, and I gave a quick update including what I had interpreted as depression after watching John over the last two weeks.

Together we went into the room, and then and there, for the first time I saw a glimmer of hope in John’s eyes. For twenty minutes Dr. Selby questioned John, and to my surprise, full sentences and explanations came as answers. I realized that all this time, John just wanted some sort of normalcy in his life. None of the questions asked of him had anything to do with his treatment or its side effects at all, instead the questions all were about sports and current events, and his family.

Humanism in medicine is defined by moments such as these, in which it becomes clear that treating a patient’s spirit and dignity goes hand-in-hand with treating the illness. In pursuit of a more humanistic service to the community, it often becomes necessary to step out of the white coat and into the patient’s world and the impact that this type of selfless service has on medical care is as invaluable as extensive clinical knowledge and cutting-edge therapies.

Taking a personal interest in each and every patient and working with them to alleviate the fear is the biggest inspiration of hope, and then backing it up with the knowledge to treat the diagnosis secures the relationship between the doctor and the patient. As physicians, we need to foster the patients’ inner strength and courage to prevail the feelings of sadness and hopelessness.

One of the most frequently asked questions that I face is: “quality of care?”

Quality of care is difficult to measure and even harder to define. In my practice I incorporate three basic principles when it comes to deciding a treatment plan: Is the right treatment being given? ; Is the treatment being given well? ; Is the patient being treated.

Is the right treatment being given is easy to answer, yes, because in today’s world, the art of evidence based medicine has guided our treatment decisions. Thousands of patients have gone into clinical trials that essentially define what we call “standard of care.”

Is the treatment being given well? Here comes the trust that a physician must have in the nursing staff, and the volume of patients that a particular center treats. Another way to improve quality of care may be to recruit patients to clinical trials. Several studies have suggested that patients treated in clinical trials have a better outcome than patients who receive similar treatment but who are not in a clinical trial.

In my field, outcome is generally judged by what we call “overall survival.” In trying to achieve this goal, we often forget what the patient is going through to buy him or her a few extra weeks. This is why “quality of life” is equally being addressed alongside the survival benefit in today’s clinical trials.

Lastly, a few words on delivering the treatment. I often find myself altering the way the treatment is given, so that the drugs have an opportunity to work, at the same time not destroying the patient’s quality of life. Physicians are so often “protocol” driven, that they often forget the toxicity of the drugs. A couple of years ago, I saw a patient who was seen by three other oncologists, two of them belonging to “large institutions.” He was told that his performance status was too poor to even administer any treatment at all, and he was told to go on to hospice. In my evaluation of the patient, I learned that the patient’s poor status was largely due to his disease burden. I came up with an alternative and modified treatment plan to deliver smaller doses of therapy, but in more frequent intervals. Within a couple of weeks, the patient started to improve and now two years later, the first words that the patient says to me every time we meet are: “thank you.”

The drugs that are available to treat the disease are relatively standard across the country, but in treating the patient, we all have to break the mold of how we were taught and learn that the patient comes first.

The above being written as a reflection on how I approach my taking care of the patient will always come first, and the disease second. We must remember that the question of “quality of life” is just as important as “quantity of life,” maybe even more so, when we as cancer specialists deal with months rather than years to make a difference in our patients’ lives.

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